Genetic risk factor of COPD

Even if an individual has never smoked or been unprotected to pollutants for an extended period of time, they can still develop COPD. Alpha-1 Antitrypsin Deficiency (AATD) is the most commonly known genetic risk factor for emphysema2. Alpha-1 Antitrypsin related COPD is caused by a deficiency of the Alpha-1 Antitrypsin protein in the bloodstream. Without the Alpha-1 Antitrypsin protein, white blood cells begin to harm the lungs and lung deterioration occurs. The World Health Organization and the American Thoracic Society suggests that each individual determined to have COPD be tested for Alpha-1.

  • Alpha1-antitrypsin
  • Alpha1-antichymotrypsin
  • Cystic fibrosis transmembrane regulator
  • Vitamin D-binding protein
  • Alpha2-macroglobulin

Related Conference of Genetic risk factor of COPD


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